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GPCR Binders, Drugs, and more Development of Macrocyclic Neurotensin Receptor Type 2 (NTS2) Opioid-Free Get your 5-day free trial TODAY!

Structure-based drug discovery of a corticotropin-releasing hormone receptor 1 antagonist using an X-ray free-electron in GPCRs as Drug Targets: Allosteric Function and Biased Signaling" at the DOT NEW October 3, 2023 | FREE

agonist determined by serial femtosecond crystallography (SFX) at the Pohang Accelerator Laboratory X-Ray Free

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FREE Symposium - IPI Surfacing (June 15, 2023) Training School on “Cell-based assays to study Adhesion (June 28 - 30, 2023) FREE 11th Adrenoceptor Symposium: Adrenoceptors and GPCR Signalling (June 30 - July

Biochemical investigations uncover that the intermediate state complex comprising β1-AR and nucleotide-free

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inflammation via enhancing NLRP3 inflammasome activation in macrophages "The putative medium-chain free

in mortality of D. armandi and also led to an increase in trehalose and a decrease in glycogen and free

attempted to close the gap by generating highly refined model structures of C5aR2, respectively in free

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GPCR Binders, Drugs, and more Design of Drug Efficacy Guided by Free Energy Simulations of the β2-Adrenoceptor Monitoring the Reversibility of GPCR Signaling by Combining Photochromic Ligands with Label-free Impedance

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Oncogenic signaling of the free-fatty acid receptors FFA1 and FFA4 in human breast carcinoma cells. Oligomerization of the heteromeric γ-aminobutyric acid receptor GABAB in a eukaryotic cell-free system

a median follow-up interval of 67.1 months, a significant trend towards reduced distant metastasis-free

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coupling  is the most suited for bioconjugation with proteins, DNA, etc, thanks to its reaction with the free

FREE Symposium - IPI Surfacing (June 15, 2023) Training School on “Cell-based assays to study Adhesion (June 28 - 30, 2023) FREE 11th Adrenoceptor Symposium: Adrenoceptors and GPCR Signalling (June 30 - July

fluorescent label upon receptor binding, thus does not require the physical separation of the bound and free due to the ratiometric nature of the assay, the FA signal depends on the concentration of both the free Therefore, FA requires sufficient receptor concentration to achieve free achieve depletion of free fluorescent

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investigating the functional impact of other components of the Gαi3 heterotrimers Activation/Deactivation Free-Energy