top of page

Search Results

Results found for "preclinical pharmacology"

  • 📰 GPCR Weekly News, April 1 to 7, 2024

    Samuel Hoare on Advanced data analysis for GPCR pharmacology, which will be held on Thursdays between , 2024 | 11th Adhesion GPCR Workshop July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology Research Unit Postdoctoral Scholar – Synaptic physiology, optical imaging, substance use disorder, pharmacology Research Fellow Postdoctoral Fellow – Molecular Pharmacology of Feeding Behavior Join Dr.

  • 📰 GPCR Weekly News, January 30 to February 5, 2023

    Pharmacological characterization of novel small molecule agonists and antagonists for the orphan receptor (June 4 - 8, 2023). 2023 Molecular Pharmacology (GRS) Seminar GRC. (June 10 - 11, 2023). (June 11 - 16, 2023). 19th World Congress of Basic & Clinical Pharmacology 2023. PhD student at Department of Drug Design and Pharmacology Software / database development postdoc at the Department of Drug Design and Pharmacology Postdoc in Bioinformatics/Data Science at Department

  • How a Failed Med School Dream Sparked a GPCR Biotech Revolution

    His work spans deep academic research, startup life, and the application of machine learning and pharmacology Superluminal Medicines: AI/ML Meets GPCR Pharmacology As Ajay continued to explore how GPCR signaling Despite decades of progress in structural biology and pharmacology, predicting how  a GPCR will respond computationally predictable, Ajay and his team are working to reduce the time and cost of developing new, more precise The ability to ask precise, translational questions is just as important as having technical expertise

  • Accelerating GPCR Drug Discovery

    For over two decades, my work has centered on GPCR pharmacology . My Approach: Biology, Execution, Systems My consulting approach uniquely blends deep pharmacology expertise

  • 📰 GPCR Weekly News - January 2 to 8, 2023

    Pharmacological Profiling of a Brugia malayi Muscarinic Acetylcholine Receptor as a Putative Antiparasitic Deadline February 12, 2023 Current Technologies To Understand G-Protein-Coupled Receptor Molecular Pharmacology June 4-8,2023. 2023 Molecular Pharmacology (GRS) Seminar GRC. June 10 - 11. June 11-16, 2023. 19th World Congress of Basic & Clinical Pharmacology 2023. July 2 - 7. Biotechnology and Biological Sciences Doctoral Training Programme Senior QM Manager Director of Molecular Pharmacology

  • 📰 GPCR Weekly News, May 29 to June 4, 2023

    This week, we would like to highlight two new publications: Pharmacological hallmarks of allostery at We look forward to seeing you in a few days at the Molecular Pharmacology GRC and the associated Molecular Pharmacology GRS in Switzerland. Pharmacological inhibition of neuropeptide Y receptors Y1 and Y5 reduces hypoxic breast cancer migration Structural and Molecular Insights into GPCR Function Pharmacological hallmarks of allostery at the M4

  • High-Content Screening for GPCR Programs: Overcoming Assay Limitations with Fluorescent Ligands

    where receptor trafficking, spatial dynamics, and context-dependent signaling significantly influence pharmacology for Modern Screening Needs Radioligand binding assays have historically been the standard for GPCR pharmacology , preserving receptor conformation, trafficking, and native membrane context—key variables for GPCR pharmacology High-Content Binding Assays In CB2-expressing HEK cells, the fluorescent ligand CELT-331  produces precise For teams working in GPCR pharmacology or cannabinoid research, these tools accelerate hit validation

  • Targeted Drug Design through GPCR Mutagenesis: Insights from β2AR

    The study focused on two critical pharmacological properties: efficacy and potency. β2AR residues that influence efficacy and potency, pharmaceutical researchers can create drugs that precisely distinction is essential for designing drugs that selectively target these residues to achieve desired pharmacological The identification of pharmacologically significant residues enables more accurate predictions of how

  • Why Sokhom Pin Never Left GPCRs, Even When Everyone Else Did

    refining assays, exploring signaling bias, and building a robust knowledge base in one of the most pharmacologically

  • Mechanism vs. Assumption: A Model-First Path to Getting GPCR MoA Right

    That’s precisely what Terry’s Corner delivers every week: practical tools from Dr. Associate; Senior Scientist, Data Science—curated roles aligned to GPCR discovery and translational pharmacology GPCR scientists, translational pharmacologists, biotech discovery teams, platform company leaders, and Access this week’s full Premium Edition here ➤ What our members say 🗣️ "The best pharmacology teacher Also super-valuable for those of us learning how to teach pharmacology." — DrGPCR University Attendee

  • 📰 GPCR Weekly News, March 11 to 17, 2024

    Terry Kenakin's "Applying Pharmacology to Drug Discovery" course at Dr. , 2024 | 11th Adhesion GPCR Workshop July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology Research Unit Postdoctoral Scholar – Synaptic physiology, optical imaging, substance use disorder, pharmacology Research Fellow Postdoctoral Fellow – Molecular Pharmacology of Feeding Behavior Director of Laboratory

  • 📰 GPCR Weekly News

    GPCRs in Neuroscience CGRP physiology, pharmacology, and therapeutic targets: Migraine and beyond. Exploring pharmacological inhibition of Gq/11 as an analgesic strategy. Current Technologies To Understand G-Protein-Coupled Receptor Molecular Pharmacology. June 4-8,2023. 2023 Molecular Pharmacology (GRS) Seminar GRC. June 10 - 11. June 11-16, 2023. 19th World Congress of Basic & Clinical Pharmacology 2023. July 2 - 7.

  • The Hidden Driver of GPCR Drug Success: Why Target Residence Time Matters More Than You Think

    Understand the synergistic mechanisms driving the escalating opioid crisis and the crucial role of GPCR pharmacology Problem Solved:  Gain a deeper understanding of the pharmacological underpinnings of opioid overdose, Listen now to understand how two mechanisms intersect—and why pharmacologists are critical in addressing GPCR scientists, translational pharmacologists, biotech discovery teams, and decision-makers who need Access this week’s full Premium Edition here ➤ What our members say 🗣️ “The best pharmacology teacher

  • ⛵Sailing the GPCR Seas: Your Weekly Research Voyage! ⦿ Nov 11 - 17, 2024

    Conference November 26 - 28, 2024 | GPCRs-Targeted Drug Discovery Summit Europe December 10 - 12, 2024 | Pharmacology | BIO International Convention 2025 July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology Principal Scientist, Medicinal Chemistry PhD fellowship in GPCR mechanosensing Senior Scientist, GPCR Pharmacology Research Associate - Professor Graeme Milligan Postdoc in Molecular Pharmacology - The Hauser Group

  • 📰 GPCR Weekly News, February 26 to March 3, 2024

    GPCR University Course, ‘Applying Pharmacology to Drug Discovery,’ led by Dr. , 2024 | 11th Adhesion GPCR Workshop July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology Research Unit Postdoctoral Scholar – Synaptic physiology, optical imaging, substance use disorder, pharmacology Research Fellow Postdoctoral Fellow – Molecular Pharmacology of Feeding Behavior Director of Laboratory

  • Science Needs Rigor, But Also Joy

    “Explaining pharmacology to a new student makes you relearn the basics. It sharpens everything.”

  • The Hidden Cost of Ambition in Biotech Leadership

    A strong preclinical signal opens adjacent therapeutic areas. Not because the science is flawed, but because the trajectory is less precise. 👉 The important distinction

  • Illuminating GPCR Research: FRET and BRET-Based Sensors Shed Light on Cellular Signaling

    significant advantages of FRET and BRET-based sensors is their ability to provide real-time readouts of pharmacological cellular processes, but also hold immense promise in accelerating drug discovery efforts by enabling the precise characterization of pharmacological interventions in real time. Salahpour, A., et al., BRET biosensors to study GPCR biology, pharmacology, and signal transduction.  Biochemical Pharmacology, 2024. 222: p. 116119. 9.     

  • 📰 GPCR Weekly News

    GPCR Activation and Signaling Molecular Mechanisms of PTH/PTHrP class B GPCR Signaling and Pharmacological Deadline February 12, 2023 Current Technologies To Understand G-Protein-Coupled Receptor Molecular Pharmacology June 4-8,2023. 2023 Molecular Pharmacology (GRS) Seminar GRC. June 10 - 11. June 11-16, 2023. 19th World Congress of Basic & Clinical Pharmacology 2023. July 2 - 7.

  • Molecular creativity in drug discovery

    Innovative Approaches in GPCR Drug Discovery: Designing Precise Solutions for GPCR Challenges. Welcome GPCR Fans, Most pharmacologists are trained to chase targets. Upcoming events:  Global GPCR summits and pharmacology forums shaping 2026 priorities. From cAMP to femtomolar ligands, she unpacks a career at the edge of precision signaling. Innovation : Her lab model at Monash is shaping the next generation of GPCR scientists. 👉 Dive into spatial pharmacology

  • Lab Leadership Without Ego: How Sokhom Pin Built the Happiest Team at Alkermes

    He was tasked with building an in vitro pharmacology group from scratch , including infrastructure, hiring

  • 📰 GPCR Weekly News, October 23 to 29, 2023

    Cytokines GPCR Jobs NEW Staff Scientist (AC-TAP) in Database Development at Department of Drug Design and Pharmacology Sciences NEW Octant Apprentice Head of Human Resource Business Partners Senior Scientist, In vitro pharmacology - Crinetics Pharmaceuticals Senior Director, In vitro pharmacology - Crinetics Pharmaceuticals In vivo Antibody Discovery Research Scientist In Vitro Biologist/Molecular Pharmacologist Explore Dr.

  • 📰 GPCR Weekly News, January 23 to 29, 2023

    Reviews, GPCRs, and more Pharmacological Profiling of a Brugia malayi Muscarinic Acetylcholine Receptor (June 4 - 8, 2023). 2023 Molecular Pharmacology (GRS) Seminar GRC. (June 10 - 11, 2023). (June 11 - 16, 2023). 19th World Congress of Basic & Clinical Pharmacology 2023. , biophysics of transporters and GPCRs Chief of Staff Postdoctoral Fellow, Biochemical And Cellular Pharmacology

  • 📰 GPCR Weekly News, January 16 to 22, 2023

    Deadline February 12, 2023 Current Technologies To Understand G-Protein-Coupled Receptor Molecular Pharmacology (June 4 - 8, 2023). 2023 Molecular Pharmacology (GRS) Seminar GRC. (June 10 - 11, 2023). (June 11 - 16, 2023). 19th World Congress of Basic & Clinical Pharmacology 2023. , biophysics of transporters and GPCRs Chief of Staff Postdoctoral Fellow, Biochemical And Cellular Pharmacology

  • 📰 GPCR Weekly News, June 26 to July 2, 2023

    Adhesion GPCRs A screen of pharmacologically active compounds to identify modulators of the Adgrg6/Gpr126 Meetings, and Webinars NEW ERNEST ECI Zoominar (July 6, 2023) 19th World Congress of Basic & Clinical Pharmacology Transport Proteins (March 24 - 29, 2024) GPCR Jobs NEW Research Scientist/Senior Scientist I - Molecular Pharmacology Medical Affairs NEW Associate Director / Director, Clinical Operations Professor in Cardiovascular Pharmacology

  • 📰 GPCR Weekly News, April 3 to 9, 2023

    subset-specific receptor expression in Caenorhabditis elegans. β- Arrestins: Structure, Function, Physiology, and Pharmacological (April 20 - 21, 2023) Swiss Biotech Day (April 24 - 25, 2023) NEW ASPET 2023 - American Society for Pharmacology (June 4 - 8, 2023). 2023 Molecular Pharmacology (GRS) Seminar GRC. (June 10 - 11, 2023). Adrenoceptors and GPCR Signalling (June 30 - July 1, 2023) 19th World Congress of Basic & Clinical Pharmacology Clinical Research PostDoctoral Associate PostDoctoral Position Team Lead protein production and profiling Pharmacologist

  • 📰 GPCR Weekly News - January 9 to 15, 2023

    Deadline February 12, 2023 Current Technologies To Understand G-Protein-Coupled Receptor Molecular Pharmacology (June 4-8, 2023). 2023 Molecular Pharmacology (GRS) Seminar GRC. (June 10 -11, 2023). (June 11-16, 2023). 19th World Congress of Basic & Clinical Pharmacology 2023. (July 2 - 7). Biotechnology and Biological Sciences Doctoral Training Programme Senior QM Manager Director of Molecular Pharmacology

  • Orthosteric Binding Experiments: How to Avoid the Most Common Data Pitfalls

    Orthosteric binding experiments remain a cornerstone of pharmacology, but they demand rigor. Modern computation handles raw nonlinear data precisely, whereas transforms distort error, compress dynamic Complex Two-Stage Biology Behind Orthosteric Binding GPCR pharmacology rarely follows the neat Langmuir Why Terry’s Corner Weekly pharmacology sessions with Dr. Built for pharmacologists strengthening fundamentals, program teams navigating bottlenecks, and leaders

  • 📰 GPCR Weekly News

    Current Technologies To Understand G-Protein-Coupled Receptor Molecular Pharmacology. June 4-8,2023. 2023 Molecular Pharmacology (GRS) Seminar GRC. June 10 - 11. June 11-16, 2023. 19th World Congress of Basic & Clinical Pharmacology 2023. July 2 - 7.

  • 📰 GPCR Weekly News, May 8 to 14, 2023

    in Cardiology, Endocrinology, and Taste Molecular Mechanisms of PTH/PTHrP Class B GPCR Signaling and Pharmacological Diagnosed with WHIM Syndrome GPCR Events, Meetings, and Webinars ASPET 2023 - American Society for Pharmacology (June 4 - 8, 2023). 2023 Molecular Pharmacology (GRS) Seminar GRC. (June 10 - 11, 2023). Adrenoceptors and GPCR Signalling (June 30 - July 1, 2023) 19th World Congress of Basic & Clinical Pharmacology

bottom of page