Search Results

This $60,000 grant from Diabetes Research WA will assist the Perkins' Molecular Endocrinology and Pharmacology

The course covers basic pharmacology in four weekly segments. , 2024 | 11th Adhesion GPCR Workshop July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology

The course covers basic pharmacology in four weekly segments. Only ten spots remain. , 2024 | 11th Adhesion GPCR Workshop July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology

(June 4 - 8, 2023). 2023 Molecular Pharmacology (GRS) Seminar GRC. (June 10 - 11, 2023). Adrenoceptors and GPCR Signalling (June 30 - July 1, 2023) 19th World Congress of Basic & Clinical Pharmacology

chaperones to improve the folding and stability of the mutant receptor is one of the most promising pharmacological

We demonstrate by pharmacologic inhibition of GRK2/3-mediated phosphorylation of the chemokine receptor

bona fide agonist of PAR2 that uniquely modulates PAR2-mediated cellular signaling and is a useful pharmacological

The development of new CB2-related pharmacological and genetic tools, including the first small molecule

for substrate linear polyubiquitination GPCR Binders, Drugs, and more Dual allosteric and orthosteric pharmacology 2024 | 9th GPCRs in Medicinal Chemistry July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology

In this study Marsango et al. address two key questions in GPR84 biology and pharmacology: 1. how GPR84 ligands (Pillaiyar et al., 2018) with biased properties which can help to better elucidate the molecular pharmacology

Finally, we validated A2BAR as a potential pharmacological tool in CRC, using selective antagonists,

perception, and thought, and have the activation of serotonin (5-HT) 2A receptors (5-HT2A Rs) as a main pharmacological

Here, GPR15L(25-81) and GPR15L(71-81) are used as pharmacological tool compounds to delineate the GPR15

The course covers basic pharmacology in four weekly segments. Only 14 out of 20 spots remain. , 2024 | 11th Adhesion GPCR Workshop July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology

evaluate parathyroid hormone (PTH) and PTH-related protein (PTHrP) ligands and analogues for their pharmacologic

Despite considerable advances in pharmacological treatment, HF represents a severe clinical and social

Despite its therapeutic potential, CB2 pharmacology remains difficult to interrogate with confidence. For researchers working in cannabinoid pharmacology, inflammation, or GPCR-mediated analgesia, these

They can also further pharmacological and structural studies, as they can be used to determine receptor Br J Pharmacol. 2020 Mar;177(5):978-991. doi: 10.1111/bph.14953.

Much of the understanding of psychedelic pharmacology is derived from rodent models, but most of this

provide proof of concept for the development of safer GPCR-targeting therapeutics with more directed pharmacological

Biased pharmacological modulators provide potential therapeutic benefits, including greater pharmacodynamic

The pharmacological profiles and mechanistic insights of our study provide clues for the future design

non-medically for euphoric feelings and medically for pain relief, although the last one comes with pharmacological pathophysiological significance in pain, addiction and depression opioid receptors represent important pharmacological

together, these results will benefit further investigations to determine physiological functions and pharmacological

future topics Access to the study group Whether you’re in hit-to-lead, lead optimization, or clinical pharmacology

(June 4 - 8, 2023). 2023 Molecular Pharmacology (GRS) Seminar GRC. (June 10 - 11, 2023). Adrenoceptors and GPCR Signalling (June 30 - July 1, 2023) 19th World Congress of Basic & Clinical Pharmacology

Terry's Corner - The Truth About Allosteric Displacement Allosteric binding isn’t just a twist in the pharmacology

Activation of melatonin MT2 receptors with either pharmacological concentrations of melatonin (10-100

agricultural settings inspired him to train in veterinary medicine, where he was introduced to physiology and pharmacology

This innovation emerged from years of foundational work in photophysics and GPCR pharmacology.