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We’ve curated 18 GPCR papers, 8 industry news, and 2 GPCR job offers! The course covers basic pharmacology in four weekly segments. Only ten spots remain. GPCR Complimentary one-year Dr. GPCR Ecosystem Premium memberships, a $250 saving Access to Dr. World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Postdoctoral Fellow NEW Research GPCR Ecosystem

The course covers basic pharmacology in four weekly segments. Only 12 out of 20 spots remain. GPCR Access to Dr. protein selectivity revealed by structural pharmacology Industry News The Adrenaline Puzzle Solved: World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Postdoctoral Scientist NEW Principal GPCR Ecosystem

Adhesion GPCR Consortium: The 11th Adhesion GPCR Workshop. World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs HIGHLIGHT Principal Scientist, In vitro pharmacology Senior Scientist - Receptor Pharmacology Postdoctoral Scientist Senior Research Associate /Associate Scientist, Protein Science Post-Doctoral Fellow—Pharmacology/Cell Biology/Biochemistry Post GPCR Ecosystem

GPCR Podcast Episode 154 of the Dr. World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs HIGHLIGHT Principal Scientist, In vitro pharmacology Senior Scientist - Receptor Pharmacology PostDoctoral Scientist Senior Research Associate /Associate Scientist, Protein Science Post-Doctoral Fellow—Pharmacology/Cell Biology/Biochemistry Post GPCR Ecosystem

news, and 2 GPCR job offers! The course covers basic pharmacology in four weekly segments. Only 14 out of 20 spots remain. GPCR Access to Dr. World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Postdoctoral Scholar - O’Neill GPCR Ecosystem

Hi GPCR lovers! This comprehensive course covers fundamental pharmacology in four weekly segments, delving into Agonists , and more Structure, function and drug discovery of GPCR signaling Illuminating the understudied GPCR-ome World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Postdoctoral Fellow NEW Post-Doc GPCR Ecosystem

While GPCRs can exist as monomers, some types, like class C GPCRs, are obligate dimers, either as homodimers affect signaling pathways in class A dopamine receptors like D1/D2 and D1/D3, which exhibit distinct pharmacological Class B1 GPCRs are an important subclass of GPCRs that include 15 receptors involved in regulating body for our understanding of GPCR function and signal transduction. Mol Pharmacol, 2012. 81 (3): p. 309-18. 9.         

Hello GPCR people! We have great news! Take a few minutes, and dive into our GPCR coverage! We welcome GPCR paper suggestions! Adhesion GPCRs The Posttraumatic Increase in the Adhesion of GPCR EMR2/ ADGRE2 to Circulating Neutrophils in Medicinal Chemistry July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology 2026 GPCR Ecosystem

GPCR Symposia 2023. Adhesion GPCRs CryoEM structures of adhesion in GPCR CD97: Filling in some of the gaps GPCR Activation Binders, Drugs, and more Dual allosteric and orthosteric pharmacology of synthetic analog cannabidiol-dimethylheptyl in Medicinal Chemistry July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology 2026 GPCR Ecosystem

September 2022 "G protein‐coupled receptors (GPCRs) are valuable therapeutic targets for many diseases A central question of GPCR drug discovery is to understand what determines the agonism or antagonism ligands made interactions with W2866.48×48 and Y3167.43×42, both residues considered to be important in GPCR detailed structure‐activity relationship that identifies small changes to the ligands that invert their pharmacological Read more at the source #DrGPCR #GPCR #IndustryNews

November 2022 "Adhesion G-protein-coupled receptors (aGPCRs) play key roles in a diversity of physiologies A hallmark of aGPCR activation is the removal of the inhibitory GAIN domain and the dipping of the cleaved The structures also reveal the uncharted structural information of GPCR/G12 coupling. Taken together, our study lays the groundwork for understanding aGPCR activation and G-protein-coupling Read more at the source #DrGPCR #GPCR #IndustryNews Subscribe to the Dr. GPCR Newsletter HERE

Hi there GPCR minds! Join us for a deep dive into the world of GPCRs. GPCR Symposium for the year on GPCRs in Immunology and Oncology! Jobs NEW Staff Scientist (AC-TAP) in Database Development at Department of Drug Design and Pharmacology Sciences NEW Octant Apprentice Head of Human Resource Business Partners Senior Scientist, In vitro pharmacology - Crinetics Pharmaceuticals Senior Director, In vitro pharmacology - Crinetics Pharmaceuticals In vivo

We will be back next week with our regular weekly GPCR news digest. In the meantime, you can always check the  Classified GPCR News from the last weeks. GPCR Podcast. GPCR. Today is also the first session of our hands-on workshop with Dr. Sam Hoare. GPCR University content coming soon.

GPCR Symposium of the year on GPCRs in Immunology and Oncology! : Allosteric activation of the ERK MAPK by β-arrestin GPCR Binders, Drugs, and more Pharmacologically Jobs Head of Human Resource Business Partners Senior Scientist, In vitro pharmacology - Crinetics Pharmaceuticals Senior Director, In vitro pharmacology - Crinetics Pharmaceuticals In vivo Antibody Discovery Research GPCR Ecosystem

Read more at the source #DrGPCR #GPCR #IndustryNews Subscribe to the Newsletter HERE

GPCR podcast with Dr. Nicole (Nicki) Perry-Hauser is now available What a fun chat! GPCR Ecosystem paid membership to enjoy everything Dr. GPCR has! ➡️https://bit.ly/3TCJVQQ #gpcr #drgpcr

Adhesion GPCRs Piconewton Forces Mediate GAIN Domain Dissociation of the Latrophilin-3 Adhesion GPCR Unveiling Mechanical Activation: GAIN Domain Unfolding and Dissociation in Adhesion GPCRs GPCR Activation Jobs NEW Head of Human Resource Business Partners Senior Scientist, In vitro pharmacology - Crinetics Pharmaceuticals Senior Director, In vitro pharmacology - Crinetics Pharmaceuticals In vivo Antibody GPCR Ecosystem

Hello GPCR people! Check out our GPCR roundup now, and be the first to read! GPCR Newsletter to get more info! Jobs NEW Senior Scientist, In vitro pharmacology - Crinetics Pharmaceuticals NEW Senior Director, In vitro pharmacology - Crinetics Pharmaceuticals In vivo Antibody Discovery Research Scientist In Vitro GPCR Ecosystem

AlphaFold, homology modeling was the most common method for predicting G protein-coupled receptor (GPCR similarity to available templates, homology models tend to be less accurate, a notable challenge for GPCRs GPCRs are dynamic, switching between multiple conformations, and many have only distant homologs with The introduction of AlphaFold2 marked a major advancement in the field of GPCR structure prediction. While AlphaFold2’s ability to predict static structures was groundbreaking, however, GPCRs are highly

GPCR University Course, ‘Applying Pharmacology to Drug Discovery,’ led by Dr. GPCR Partnered Events April 22 - 23, 2024 | Endocrine Metabolic GPCRs Join the Endocrine Metabolic GPCRs World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs Senior Scientist- Internal Medicine Research Unit Postdoctoral Scholar – Synaptic physiology, optical imaging, substance use disorder, pharmacology Research Fellow Postdoctoral Fellow – Molecular Pharmacology of Feeding Behavior Director of Laboratory

Reading Materials Access to the private group Certificate Explore: Key metrics for assessing ligand pharmacology activity Unique drug profiles from new ligands and GPCR behaviors GPCR Event Highlight Join us in vibrant Let’s dive into the Classified GPCR News from July 22 to 28, 2024 GPCR Activation and Signaling Activating World Congress of Basic and Clinical Pharmacology GPCR Jobs NEW Postdoctoral Position NEW Postdoctoral GPCR Ecosystem

network located on intracellular loop 2 that is subject to RNA editing, which differentially affects GPCR Read more at the source #DrGPCR #GPCR #IndustryNews

GPCR Symposium about 'GPCRs as Therapeutic Modalities' rocked it! GPCR Newsletter! Dive into the Classified GPCR News from September 18th to 24th, 2023. GPCR Activation and Signaling Rules and mechanisms governing G protein coupling selectivity of GPCRs Technician II - Surgery Post-Doc Research Associate Research Technician Senior Research Associate, In Vitro Pharmacology GPCR Ecosystem

Hello GPCR people! Check out our GPCR roundup now, and be the first to read! GPCR Symposium on 'GPCRs as Therapeutic Modalities' with Richa Tyagi, Dr. Terry Kenakin, Dr. GPCR Activation and Signaling Characterization of the real-time internalization of nine GPCRs reveals Surgery NEW Post-Doc Research Associate NEW Research Technician Senior Research Associate, In Vitro Pharmacology GPCR Ecosystem

that the affinity of Fzd for Dvl was not affected by Wnt ligands, in contrast to other members of the GPCR Read more at the source #DrGPCR #GPCR #IndustryNews

GPCR Symposium on ''GPCRs as Therapeutic Modalities' Share your project with a 1-minute abstract video GPCR Newsletter for more insights! Program Acquired by Vertex Call for GPCR Papers opnMe GPCR Route 66+ project. Jobs NEW Senior Research Associate, In Vitro Pharmacology - Crinetics Pharmaceuticals NEW Postdoc In GPCR Ecosystem

GPCR Symposia Our upcoming symposium on March 15th is about GPCR activation and signaling. GPCR University This week marks the beginning of our first Dr.GPCR University course, 'Applying Pharmacology Webinars February 11 - 14, 2024 | 2024 BPS Annual Meeting February 20, 2024 | Career Opportunities in Pharmacology World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Postdoctoral Fellowship- Mechanistic GPCR Ecosystem

Human cells express over 800 G-protein-coupled receptors (GPCRs) to facilitate communication with the Capturing the dynamics of GPCR activation has always been a challenge because G protein activation in With this high-resolution, dynamic view of GPCR activation, scientists can better tackle diseases by Beyond GPCRs, the methods and insights from this study can be applied to other fast, transient biological Time-resolved cryo-EM of G-protein activation by a GPCR. Nature (2024).

February 2022 Septerna emerges with $100M to spark 'second golden age' of prolific drug target GPCR with Better known as GPCR, the fruitful research space has led to more than 700 approved drugs over previous The company's co-founder, GPCR pioneer and Nobel laureate Robert Lefkowitz, M.D., has 50 years of experience Read more at the source #DrGPCR #GPCR #IndustryNews

October 2022 "Understanding the activation of G protein-coupled receptors (GPCRs) is of paramount importance Although many cardiovascular GPCRs have been extensively studied as model receptors for decades, new Here, we review how nanobodies have been adopted to elucidate the structure, pharmacology, and signaling of cardiovascular GPCRs, resolving long-standing mysteries and revealing unexpected mechanisms. Read more at the source #DrGPCR #GPCR #IndustryNews