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Results found for "opioid pharmacology"

  • Orthosteric Binding Experiments: How to Avoid the Most Common Data Pitfalls

    Orthosteric binding experiments remain a cornerstone of pharmacology, but they demand rigor. Complex Two-Stage Biology Behind Orthosteric Binding GPCR pharmacology rarely follows the neat Langmuir Why Terry’s Corner Weekly pharmacology sessions with Dr. Built for pharmacologists strengthening fundamentals, program teams navigating bottlenecks, and leaders

  • GPCR Allosteric Modulation: Why Allostery is the Engine of Drug Discovery

    Terry’s Pharmacology Corner  delivers trusted, razor-sharp insight to help drug discovery professionals Unlock “GPCRs as Allosteric Machines” Now Only in Terry’s Corner Why Terry’s Corner Terry’s Pharmacology growing, curated on-demand library Opportunities to shape future topics Built for discovery-phase teams, pharmacologists

  • How Schild Analysis Protects Your Conclusions in GPCR Research

    Upcoming events:  GPCR-TDD Europe; Pharmacology 2026. Researchers navigating complex datasets, balancing innovation with assay rigor, or working across chemistry–pharmacology–physiology GPCR scientists, translational pharmacologists, biotech discovery teams, and decision-makers who need

  • 📰 GPCR Weekly News, October 16 to 22, 2023

    transduction at GPCRs: Allosteric activation of the ERK MAPK by β-arrestin GPCR Binders, Drugs, and more Pharmacologically Chemotactic Cytokines GPCR Jobs Head of Human Resource Business Partners Senior Scientist, In vitro pharmacology - Crinetics Pharmaceuticals Senior Director, In vitro pharmacology - Crinetics Pharmaceuticals In vivo Antibody Discovery Research Scientist In Vitro Biologist/Molecular Pharmacologist Senior Vice President

  • 📰 GPCR Weekly News, March 13 to 19, 2023

    Pharmacological characterization of novel small molecule agonists and antagonists for the orphan receptor G protein-coupled receptor pharmacology - insights from mass spectrometry. (June 4 - 8, 2023). 2023 Molecular Pharmacology (GRS) Seminar GRC. (June 10 - 11, 2023). Adrenoceptors and GPCR Signalling (June 30 - July 1, 2023) 19th World Congress of Basic & Clinical Pharmacology

  • How to Design GPCR Drugs That Work in Vivo: Strategy, Tools, and Insights

    This Week’s GPCR Intelligence: From Set-Point Pharmacology to No-Wash Internalization Assays This week structure-encoded location-biased signaling, GPCR signaling in metabolism, and future directions in biased ligand pharmacology GPCR scientists, translational pharmacologists, biotech discovery teams, and decision-makers who need

  • Ermium Therapeutics has constituted its SAB

    Therapeutics Announces the Formation of a Scientific Advisory Board comprising international leaders in GPCRs pharmacology

  • From One to Many: How a GPCR Curiosity Became a Field-Wide Toolkit

    that these small, single-transmembrane proteins weren’t just chaperones; they actively shaped receptor pharmacology

  • How to Use Statistical Methods to Strengthen Every GPCR Drug Discovery Decision

    for proteins: Tracking the motions of cell receptors; A Better Way to Treat Obesity; Unlocking the pharmacological climbing the spotlight; new tools tracking receptor motion; obesity drug strategies shifting; antibody pharmacology Ajay Yekkirala shares the journey from academic pharmacologist to biotech entrepreneur—bridging curiosity GPCR scientists, translational pharmacologists, biotech discovery teams, and decision-makers who need

  • 📰 GPCR Weekly News, February 5 to 11, 2024

    GPCR University Last week marked the beginning of our first Dr.GPCR University course, 'Applying Pharmacology Board of Directors GPCR Events, Meetings, and Webinars February 20, 2024 | Career Opportunities in Pharmacology , 2024 | 11th Adhesion GPCR Workshop July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology

  • 📰 GPCR Weekly News, August 21 to 27, 2023

    Sudarshan Rajagopal and their lab team study on 'Location bias: A "Hidden Variable" in GPCR pharmacology GPCRs, and more Key Aspects of Modern GPCR Drug Discovery Location bias: A "Hidden Variable" in GPCR pharmacology Postdoc Research Associate Director, Regulatory Affairs Research Scientist/Senior Scientist I - Molecular Pharmacology

  • 📰 GPCR Weekly News, August 14 to 20, 2023

    Congrats to the GPCR Therapeutics team for their recent paper in the American College of Clinical Pharmacology Industry News 'GPCR Therapeutics' latest science paper was published by the American College of Clinical Pharmacology Postdoc Research Associate Director, Regulatory Affairs Research Scientist/Senior Scientist I - Molecular Pharmacology

  • 📰 GPCR Weekly News, May 1 to 7, 2023

    in Three Upcoming Conferences GPCR Events, Meetings, and Webinars ASPET 2023 - American Society for Pharmacology (June 4 - 8, 2023). 2023 Molecular Pharmacology (GRS) Seminar GRC. (June 10 - 11, 2023). Adrenoceptors and GPCR Signalling (June 30 - July 1, 2023) 19th World Congress of Basic & Clinical Pharmacology

  • Advantages of Fluorescent Probes in GPCR Assays

    They can also further pharmacological and structural studies, as they can be used to determine receptor Br J Pharmacol. 2020 Mar;177(5):978-991. doi: 10.1111/bph.14953.

  • GRK2 in cardiovascular disease and its potential as a therapeutic target

    Despite major advances in the field of pharmacological CVD treatments, particularly in the field of heart Additionally, GPCR dysregulation underlies multiple models of cardiac pathology, and most pharmacological

  • Assay Volume Control: Your GPCR Drug Discovery Power Lever

    See the true  pharmacology:  Lower sensitivity to uncover partial agonism and compare relative efficacy classified industry updates, priority event alerts, vetted jobs, and commentary that connects dots across pharmacology GPCR scientists, translational pharmacologists, discovery teams, and decision-makers who need fast, curated

  • Use of CRISPR/Cas9-edited HEK293 cells reveals that both conventional and novel protein kinase C...

    Our PKC KO cell lines expand the repertoire of KO HEK293A cell lines available to research GPCR pharmacology Moreover, since pharmacological tools to study PKC isozymes generally lack specificity and/or potency

  • 📰 GPCR Weekly News, January 22 to 28, 2024

    GPCR University We're thrilled to share that all spots for the Applying Pharmacology to Drug Discovery Exhibition February 11 - 14, 2024 | 2024 BPS Annual Meeting NEW February 20, 2024 | Career Opportunities in Pharmacology , 2024 | 11th Adhesion GPCR Workshop July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology

  • 📰 GPCR Weekly News, January 15 to 21, 2024

    GPCR University course, Applying Pharmacology to Drug Discovery, led by Dr. The course covers basic pharmacology in four weekly segments and is open to all with a free site membership , 2024 | 11th Adhesion GPCR Workshop July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology

  • Mapping Motion: Intermediate States, Deorphanization & Discovery

    GPCR Updates   Techniques for Effective Lead Optimization – Master pharmacology on demand   Build stronger

  • 📰 GPCR Weekly News

    Reviews, GPCRs, and more Species dependence of A3 adenosine receptor pharmacology and function. Deadline February 12, 2023 Current Technologies To Understand G-Protein-Coupled Receptor Molecular Pharmacology June 4-8,2023. 2023 Molecular Pharmacology (GRS) Seminar GRC. June 10 - 11. June 11-16, 2023. 19th World Congress of Basic & Clinical Pharmacology 2023. July 2 - 7.

  • 📰 GPCR Weekly News, March 6 to 12, 2023

    (June 4 - 8, 2023). 2023 Molecular Pharmacology (GRS) Seminar GRC. (June 10 - 11, 2023). Adrenoceptors and GPCR Signalling (June 30 - July 1, 2023) 19th World Congress of Basic & Clinical Pharmacology PhD Studentship - Integrated Approaches In Pharmacology, Computer Simulations And Machine Learning To

  • 📰 GPCR Weekly News, December 18 to 31, 2023

    The course covers basic pharmacology in four weekly segments. Only 12 out of 20 spots remain. antagonists using a nanoscale hCCR3 receptor sensor GPCR-G protein selectivity revealed by structural pharmacology , 2024 | 11th Adhesion GPCR Workshop July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology

  • 📰 GPCR Weekly News, October 2 to 8, 2023

    Conference and Exhibition June 2 - 4, 2024 | Chemotactic Cytokines GPCR Jobs NEW Senior Scientist, In vitro pharmacology - Crinetics Pharmaceuticals NEW Senior Director, In vitro pharmacology - Crinetics Pharmaceuticals In vivo Antibody Discovery Research Scientist In Vitro Biologist/Molecular Pharmacologist Senior Vice President

  • How Collaboration Drives GPCR Discoveries

    what they weren’t built for, JB’s group engineered fluorescent ligands based on known GLP-1 and GIP pharmacology They’re team problems — the kind that require chemistry, physiology, pharmacology, structural biology

  • 📰 GPCR Weekly News, July 3 to 9, 2023

    Postdoctoral Fellow, Caron Lab NEW Clinical Trial Associate Research Scientist/Senior Scientist I - Molecular Pharmacology President, Medical Affairs Associate Director / Director, Clinical Operations Professor in Cardiovascular Pharmacology

  • 📰 GPCR Weekly News, April 24 to 30, 2023

    , Ph.D. to Board of Directors GPCR Events, Meetings, and Webinars ASPET 2023 - American Society for Pharmacology (June 4 - 8, 2023). 2023 Molecular Pharmacology (GRS) Seminar GRC. (June 10 - 11, 2023). Adrenoceptors and GPCR Signalling (June 30 - July 1, 2023) 19th World Congress of Basic & Clinical Pharmacology

  • 📰 GPCR Weekly News, October 30 to November 4, 2023

    Antibody Discovery Staff Scientist (AC-TAP) in Database Development at Department of Drug Design and Pharmacology Medical Sciences Octant Apprentice Head of Human Resource Business Partners Senior Scientist, In vitro pharmacology - Crinetics Pharmaceuticals Senior Director, In vitro pharmacology - Crinetics Pharmaceuticals Explore

  • How Advanced GPCR Kinetics Sharpen Decision Making (and Save You Time)

    Career opportunities:  Snapshot of roles spanning PhD entry points to senior translational pharmacology—Protein Expression, Drug Discovery Scientist, and Staff Scientist in Molecular Pharmacology—curated with notes GPCR scientists, translational pharmacologists, biotech discovery teams, and decision-makers who need

  • 📰 GPCR Weekly News, June 12 to 18, 2023

    Adrenoceptors and GPCR Signalling (June 30 - July 1, 2023) 19th World Congress of Basic & Clinical Pharmacology Ion Channels, and Transport Proteins (March 24 - 29, 2024) GPCR Jobs NEW Professor in Cardiovascular Pharmacology

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