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Targeting Intracellular Allosteric Sites in GPCRs

Nov 1, 20234 min read

Decoding β-Arrestins: from Structure to function

Aug 21, 20235 min read

Structural landscape of the Chemokine Receptor system

Jun 28, 20237 min read

Artificial intelligence – faster, smarter, cheaper GPCR drug discovery

May 16, 20235 min read

Emerging approaches for decoding neuropeptide transmission

Nov 1, 20221 min read

Location bias contributes to functionally selective responses of biased CXCR3 agonists

Nov 1, 20221 min read

Deciphering the signaling mechanisms of β-arrestin1 and β-arrestin2 in regulation of cancer cell...

Nov 1, 20221 min read

Structure-Based Discovery of Negative Allosteric Modulators of the Metabotropic Glutamate Receptor 5

Nov 1, 20221 min read

Structural insights into adhesion GPCR ADGRL3 activation and Gq, Gs, Gi, and G12 coupling

Nov 1, 20221 min read

Conservation of Allosteric Ligand Binding Sites in G-Protein Coupled Receptors

Nov 1, 20221 min read

Dimerization of β2-adrenergic receptor is responsible for the constitutive activity subjected to inv

Nov 1, 20221 min read

High hedgehog signaling is transduced by a multikinase-dependent switch controlling the...

Oct 1, 20221 min read

Structure of the vasopressin hormone-V2 receptor-β-arrestin1 ternary complex

Oct 1, 20221 min read

Dual loss of regulator of G protein signaling 2 and 5 exacerbates ventricular myocyte arrhythmias...

Oct 1, 20221 min read

Mechanistic basis of GPCR activation explored by ensemble refinement of crystallographic structures

Oct 1, 20221 min read

Increased Anxiety-like Behaviors in Adgra1-/- Male But Not Female Mice are Attributable to...

Oct 1, 20221 min read

Dimerization of β2-adrenergic receptor is responsible for the constitutive activity subjected to...

Oct 1, 20221 min read

Structural view of G protein-coupled receptor signaling in the retinal rod outer segment

Oct 1, 20221 min read

Case Report of a Juvenile Patient with Autism Spectrum Disorder with a Novel Combination of Copy...

Oct 1, 20221 min read

Discovery and In Vivo Evaluation of ACT-660602: A Potent and Selective Antagonist of the Chemokine..

Oct 1, 20221 min read

Recurrent hypoglycemia increases hepatic gluconeogenesis without affecting glycogen metabolism or sy

Oct 1, 20221 min read

Reversible Photocontrol of Dopaminergic Transmission in Wild-Type Animals

Oct 1, 20221 min read

Nanobodies as Probes and Modulators of Cardiovascular G Protein-Coupled Receptors

Oct 1, 20221 min read

Structural basis of adhesion GPCR GPR110 activation by stalk peptide and G-proteins coupling

Oct 1, 20221 min read

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