Insights That Move the GPCR Field Forward

September 2022 "Sound is converted by hair cells in the cochlea into electrical signals, which are transmitted by spiral ganglion neurons...

September 2022 "Background Cancer driver genes are usually ranked by mutation frequency, which does not necessarily reflect their driver...

September 2022 "The bioactive lysophospholipid sphingosine-1-phosphate (S1P) acts via five different subtypes of S1P receptors (S1PRs) -...

September 2022 Isoforms of GPR35 have distinct extracellular N-termini that allosterically modify receptor-transducer coupling and...

September 2022 Roles of Focal Adhesion Kinase PTK2 and Integrin αIIbβ3 Signaling in Collagen- and GPVI-Dependent Thrombus Formation under...

September 2022 Cell Surface Calcium-Sensing Receptor Heterodimers: Mutant Gene Dosage Affects Ca 2+ Sensing but Not G Protein Interaction...

September 2022 "Melanocortin 4 receptor (MC4R) is part of the leptin-melanocortin pathway and plays an essential role in mediating energy...

September 2022 High GPER expression in triple-negative breast cancer is linked to pro-metastatic pathways and predicts poor patient...

September 2022 "Systemic sclerosis (SSc) is a systemic autoimmune disease with the key features of inflammation, vasculopathy and...

September 2022 "GPCR signaling and function depend on their associated proteins and subcellular locations. Besides G-proteins and...

September 2022 GPR84 signaling promotes intestinal mucosal inflammation via enhancing NLRP3 inflammasome activation in macrophages "The...

September 2022 Fly casting with ligand sliding and orientational selection supporting complex formation of a GPCR and a middle sized...

September 2022 Dimerization of GPCRs: Novel insight into the role of FLNA and SSAs regulating SST2 and SST5 homo- and hetero-dimer...

September 2022 "Class A (rhodopsin-like) G protein-coupled receptors (GPCRs) are constitutive phospholipid scramblases as evinced after...

September 2022 "The follicle-stimulating hormone receptor (FSHR) belongs to the glycoprotein hormone receptors, a subfamily of...

September 2022 Angiotensin-(1-7) improves cognitive function and reduces inflammation in mice following mild traumatic brain injury...

September 2022 "RNA editing is a process by which post-transcriptional changes of mRNA nucleotides alter protein function through...

September 2022 PLC-IP3-ORAI pathway participates in the activation of the MRGPRB2 receptor in mouse peritoneal mast cells "A novel mast...

September 2022 Exploiting Dependence of Castration-Resistant Prostate Cancer on the Arginine Vasopressin Signaling Axis by Repurposing...

September 2022 "Background: Colorectal cancer is the third most common cancer and requires more prognostic biomarkers for precise...

September 2022 "Yeast use the G-protein–coupled receptor signaling pathway to detect and track the mating pheromone. The...

September 2022 Lysine 101 in the CRAC Motif in Transmembrane Helix 2 Confers Cholesterol-Induced Thermal Stability to the Serotonin 1A...

September 2022 "The G-protein-coupled bile acid receptor, Gpbar1 or TGR5, is characterized as a membrane receptor specifically activated...

September 2022 "The human sweet taste receptor is a heterodimeric receptor composed of two distinct G-protein-coupled receptors (GPCRs),...