Insights That Move the GPCR Field Forward

September 2022 "GPCR signaling and function depend on their associated proteins and subcellular locations. Besides G-proteins and...

September 2022 GPR84 signaling promotes intestinal mucosal inflammation via enhancing NLRP3 inflammasome activation in macrophages "The...

September 2022 Fly casting with ligand sliding and orientational selection supporting complex formation of a GPCR and a middle sized...

September 2022 Dimerization of GPCRs: Novel insight into the role of FLNA and SSAs regulating SST2 and SST5 homo- and hetero-dimer...

September 2022 "Class A (rhodopsin-like) G protein-coupled receptors (GPCRs) are constitutive phospholipid scramblases as evinced after...

September 2022 "The follicle-stimulating hormone receptor (FSHR) belongs to the glycoprotein hormone receptors, a subfamily of...

September 2022 Angiotensin-(1-7) improves cognitive function and reduces inflammation in mice following mild traumatic brain injury...

September 2022 "RNA editing is a process by which post-transcriptional changes of mRNA nucleotides alter protein function through...

September 2022 PLC-IP3-ORAI pathway participates in the activation of the MRGPRB2 receptor in mouse peritoneal mast cells "A novel mast...

September 2022 Exploiting Dependence of Castration-Resistant Prostate Cancer on the Arginine Vasopressin Signaling Axis by Repurposing...

September 2022 "Background: Colorectal cancer is the third most common cancer and requires more prognostic biomarkers for precise...

September 2022 "Yeast use the G-protein–coupled receptor signaling pathway to detect and track the mating pheromone. The...

September 2022 Lysine 101 in the CRAC Motif in Transmembrane Helix 2 Confers Cholesterol-Induced Thermal Stability to the Serotonin 1A...

September 2022 "The G-protein-coupled bile acid receptor, Gpbar1 or TGR5, is characterized as a membrane receptor specifically activated...

September 2022 "The human sweet taste receptor is a heterodimeric receptor composed of two distinct G-protein-coupled receptors (GPCRs),...

September 2022 Divergent roles for the gut intraepithelial lymphocyte GLP-1R in control of metabolism, microbiota, and T cell-induced...

September 2022 "Glutamate is the primary excitatory neurotransmitter in the brain and plays critical roles in all aspects of neuronal...

September 2022 "Endogenous parathyroid hormone (PTH) and PTH-related peptide (PTHrP) bind to the parathyroid hormone receptor 1 (PTH1R)...

September 2022 "G-protein-coupled receptors (GPCRs) are involved in a wide array of physiological and disease functions, yet knowledge of...

September 2022 "The endocannabinoid system plays a key role in the intersection of the nervous, endocrine, and immune systems, regulating...

September 2022 "MRAP2 is a small simple transmembrane protein arranged in a double antiparallel topology on the plasma membrane. It is...

September 2022 "GPCRs are the most potential targets for drug discovery, however, their role in oncology is underappreciated and...

September 2022 "G protein-coupled receptor (GPCR) kinases (GRKs) and arrestins mediate GPCR desensitization, internalization, and...

September 2021 "Cannabinoids are abundant signaling compounds; their influence predominantly arises via engagement with the principal two...