Insights That Move the GPCR Field Forward

October 2022 GPR15 expressed in T lymphocytes from RA patients is involved in leukocyte chemotaxis to the synovium "The rheumatoid...

October 2022 "While the role of G-protein-coupled receptors (GPCR) in cancer is acknowledged, their underlying signaling pathways are...

October 2022 "Single-molecule counting techniques enable a precise determination of the intracellular abundance and stoichiometry of...

October 2022 Membrane Lipids Are an Integral Part of Transmembrane Allosteric Sites in GPCRs: A Case Study of Cannabinoid CB1 Receptor...

October 2022 "The prefrontal cortex (PFC) is a hub for cognitive control, and dopamine profoundly influences its functions. In other...

October 2022 Novel Therapies for Cardiometabolic Disease: Recent Findings in Studies with Hormone Peptide-Derived G Protein Coupled...

October 2022 "Enzymatic and cellular signalling biosensors are used to decipher the activities of complex biological systems. Biosensors...

October 2022 Network pharmacological investigation into the mechanism of Kaixinsan powder for the treatment of depression "Kaixinsan...

October 2022 "Protease activated receptors (PARs) are among the first receptors shown to transactivate other receptors: noticeably, these...

October 2022 "Numerous physiological processes in insects are tightly regulated by neuropeptides and their receptors. Although they form...

October 2022 "Lysosomes coordinate cellular metabolism and growth upon sensing of essential nutrients, including cholesterol. Through...

October 2022 Regulation of pulmonary surfactant by the adhesion GPCR GPR116/ADGRF5 requires a tethered agonist-mediated activation...

October 2022 "Over three decades of research have provided thorough insights into G protein-coupled receptor (GPCR) regulation. In a...

October 2022 Design and validation of recombinant protein standards for quantitative Western blot analysis of cannabinoid CB1 receptor...

October 2022 Genome-scale CRISPR screening reveals that C3aR signaling is critical for rapid capture of fungi by macrophages "The fungal...

October 2022 Successful prednisolone or calcimimetic treatment of acquired hypocalciuric hypercalcemia caused by biased allosteric CaSR...

October 2022 "Cannabinoid Receptor 2 (CB2) is a G protein-coupled receptor (GPCR) with considerable, though as yet unrealised,...

October 2022 "Perturbation of the endocannabinoid system can have profound effects on immune function and synaptic plasticity. Microglia...

October 2022 "The activity of dopamine neurons is dependent on both intrinsic properties and afferent projections. One potent form of...

October 2022 "Study of small molecule binding to live cells provides important information on the characterization of ligands...

October 2022 Cholesterol-Dependent Dynamics of the Serotonin1A Receptor Utilizing Single Particle Tracking: Analysis of Diffusion Modes...

October 2022 "G protein-coupled receptors (GPCRs) are of considerable interest due to their importance in a wide range of physiological...

October 2022 "Pepducins are small-lipidated peptides designed from the intracellular loops of G protein-coupled receptors (GPCRs) that...

October 2022 Pharmacological targeting of cGAS/STING-YAP axis suppresses pathological angiogenesis and ameliorates organ fibrosis "Organ...