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Regulator G protein Signaling (RGS) proteins are critical components of the intracellular signaling pathways that mediate the effects of...

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Glycosylation and sulfation – N-terminal PTMs on chemokine receptors The interaction of chemokine receptors with their cognate chemokine...

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With around 187 people dying every day from an opioid overdose in the U.S., combatting the opioid overdose epidemic has become a mean...

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Executive Summary This whitepaper will provide an overview of G Protein-Coupled Receptors (GPCRs) and discuss current trends in GPCR drug...

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Odorant receptors function and expression landscape Odorant receptors (ORs) belong to the G protein-coupled receptor (GPCR) family and...

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Among the different families of G-protein-coupled receptors (GPCRs), adhesion GPCRs (aGPCRs) represent the second most abundant in humans....

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Transmembrane domains of GPCR dimers – a novel hot spot for drug discovery G-protein-coupled receptors (GPCRs) can form biologically...