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Insights That Move the GPCR Field Forward
Read the latest analyses, interviews, and discoveries shaping the GPCR ecosystem — from research breakthroughs to biotech strategy.
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⛵Sailing the GPCR Seas: Your Weekly Research Voyage! ⦿ Nov 11 - 17, 2024
Hoist the sails, GPCR sailors! The GPCR ship is setting sail on a grand voyage across the vast ocean of research. Dive in and explore the depths in this week's GPCR update! This Week’s Highlights: SNX9 family mediates βarrestin-independent GPCR endocytosis Valeria Robleto , Ya Zhuo , Joseph Crecelius , Sara Benzow , Adriano Marchese Cannabinoid regulation of angiotensin II-induced calcium signaling in striatal neurons Rafael Rivas-Santisteban , Ana Muñoz , Jaume Lillo , Iu Ra

GPCR News
Nov 21, 20244 min read


What's Going On with GPCRs?! Find Out in This Week's Update! ⦿ Nov 4 - 10, 2024
Hey there, curious minds! Want to know what’s buzzing in the world of GPCRs? Join us for this week’s update, where you’ll find all the latest breakthroughs and exciting developments in GPCR research. We can’t wait to share it with you! This Week’s Highlights: Harnessing Deep Mutational Scanning for Enhanced Drug Discovery Cam Sinh Lu GPCR-BSD: a database of binding sites of human G-protein coupled receptors under diverse states Fan Liu , Han Zhou , Xiaonong Li , Liangliang Zh

GPCR News
Nov 14, 20243 min read


Harnessing Deep Mutational Scanning for Enhanced Drug Discovery
Deep mutational scanning (DMS) is a powerful method for studying the functional consequences of various genetic variants within a...

Cam Sinh Lu
Nov 12, 20244 min read


Exciting GPCR Events for Next Year! + GPCR Weekly Rocket Launch ⦿ Oct 28 - Nov 3, 2024
Get your space suits on, GPCR cadets! The GPCR rocket is all fueled and ready to blast off into a galaxy of incredible advancements, now powered up with a series of cosmic GPCR events for the year ahead. It’s time to mark your calendars and save the dates—let’s make some stellar memories together! 🚀✨ This Week’s Highlights: Congrats to: Ya-Tzu Li , our notable contributor, for her superb undergrad paper along with Hao-Jen Hsu , Chun-Chun Chang , et al.  about State transi

GPCR News
Nov 7, 20245 min read


Embark on a GPCR Adventure: Your Weekly Research Expedition! | Oct 21-27, 2024
Get ready for an expedition, GPCR explorers! Embark on another exciting exploration of the unknown realms of GPCR research. Welcome back to your weekly GPCR quest! This Week’s Highlights: Congrats to: John Teye Azietaku , our great contributor, for his article Class B1 GPCR Dimerization: Unveiling Its Role in Receptor Function and Signaling Sonja Peter , Brian Bender , Chris De Graaf  for their excellent work on Comparative Study of Allosteric GPCR Binding Sites and Their Li

GPCR News
Oct 31, 20243 min read
Class B1 GPCR Dimerization: Unveiling Its Role in Receptor Function and Signaling
G protein-coupled receptors (GPCRs) are membrane-bound proteins that sense external stimuli and relay signals inside the cell, resulting...

John Teye Azietaku
Oct 29, 20243 min read


Embark on a GPCR Adventure: Your Weekly Research Expedition! | Oct 21-27, 2024
Get ready for an expedition, GPCR explorers! Embark on another exciting exploration of the unknown realms of GPCR research. Welcome back to your weekly GPCR quest! This Week’s Highlights: Congrats to: John Teye Azietaku , our great contributor, for his article Class B1 GPCR Dimerization: Unveiling Its Role in Receptor Function and Signaling Sonja Peter , Brian Bender , Chris De Graaf for their excellent work on Comparative Study of Allosteric GPCR Binding Sites and Their Lig

GPCR News
Oct 24, 20242 min read
Profiling Immune Cell and Platelet Transcriptomes
G protein-coupled receptors (GPCRs) are integral to cellular signaling, influencing a wide array of physiological processes and serving...

Monserrat Avila-Zozaya
Oct 22, 20242 min read


Discover the Hottest GPCR News of the Week: Oct 7-13, 2024!
Hey there, GPCR Enthusiasts! Ready for your GPCR quest, so bold and bright? Join us now, and let's explore with all our might! 🎇 This Week’s Highlights: Congrats to: Remi Janicot , and Mikel Garcia-Marcos for their excellent work on Protocol to investigate G protein-coupled receptor signaling kinetics and concentration-dependent responses using ONE-GO biosensors Why wait any longer to sign up for Principles of Pharmacology II ? Act fast to secure your place in our upcoming

GPCR News
Oct 17, 20244 min read


GPCR Weekly Whirlwind: Top Receptor Highlights from Sep 30 - Oct 6, 2024!
Hey there, GPCR Enthusiasts! Are you geared up for your GPCR fix of the day? Get ready to dive into some discoveries and mind-blowing breakthroughs with us! This Week’s Highlights: Congrats to: Our contributor, Cam Sinh Lu ,  who has just released an incredible article on our site and a GPCR Paper with his team: Targeted Drug Design through GPCR Mutagenesis: Insights from β2AR China M Payne ,  Cam Sinh Lu ,  Karen Gregory ,  Lauren May ,  Andrea Vernall , et al. for their f

GPCR News
Oct 10, 20244 min read


Targeted Drug Design through GPCR Mutagenesis: Insights from β2AR
After discussing the fundamentals and applications of mutagenesis in GPCR studies (Lu, 2024), a case study is essential to deepen...

Cam Sinh Lu
Oct 8, 20243 min read


GPCR Buzz of the Week | Sep 23 - 29, 2024
Welcome aboard, GPCR Crew! Let's set sail towards exciting discoveries and groundbreaking achievements together! This Week’s Highlights: Our fearless leader, Yamina Berchiche , is gearing up to rock the mic today at the 22nd Discovery on Target ! We're sending you all the good vibes and a sprinkle of birthday magic for an epic celebration! 🚀🎉 Kilian Roßmann , Joshua Levitz , Johannes Broichhagen for their excellent work on Deuteration as a General Strategy to Enhance Azobe

GPCR News
Oct 3, 20244 min read
AlphaFold’s Breakthrough in GPCR Research: Revolutionizing Discovery, Yet Awaiting Experimental Proof
Before the advent of AlphaFold, homology modeling was the most common method for predicting G protein-coupled receptor (GPCR) structures,...

Ya-Tzu Li
Oct 1, 20242 min read


📢 Early Bird Registration Ends Tomorrow! | Sep 16 - 22, 2024
Ahoy, GPCR Crew! Instead of just staying up to date, dive in, broaden your knowledge, and pave the way in the fantastic world of the GPCR field! This Week’s Highlights: Celebrating Excellence: Hyoungjun Ham , Yamina Berchiche , Thomas Sakmar , Vladimir Katanaev , Helen Su , et al. for their fantastic work on Germline mutations in a G protein identify signaling cross-talk in T cells Victoria Saca , Colin Burdette , and Thomas Sakmar for their excellent study on GPCR Biosens

GPCR News
Sep 26, 20244 min read
Biased Agonism at the GLP-1 Receptor: A Pathway to Improved Therapeutic Outcomes
Biased agonism is a phenomenon where different ligands acting on the same receptor trigger distinct signaling pathways, leading to varied...

John Teye Azietaku
Sep 23, 20244 min read


Transformative GPCR Insights: Unleash New Horizons in Science | Sep 9 - 15, 2024
Join the Future of GPCR Science - AGPCR 24 Ful Agenda Available! | Dive into groundbreaking research and cutting-edge courses.

GPCR News
Sep 19, 20244 min read


Unlock the Future of GPCR Science: Breakthroughs and Courses Await | Sep 2 - Sep 8, 2024
Dive into the latest breakthroughs in GPCR research, seize new learning opportunities, and take advantage of exclusive discounts!

GPCR News
Sep 12, 20244 min read
APEX2/AUR Biosensor: A Powerful Tool for Protein Interaction and Trafficking
Significant advancements in the cellular biology of G protein-coupled receptors (GPCRs) about a novel biosensor shed light on the...

Monserrat Avila-Zozaya
Sep 10, 20242 min read


GPCR Updates: Celebrating Breakthroughs, New Course Launches Soon, and Exclusive Discounts! | Aug 26 - Sep 1, 2024
We hope you had a fantastic Labor Day! We’re thrilled to bring you the latest updates from the GPCR world, including some exciting news...

GPCR News
Sep 5, 20245 min read


Decoding GPCR Function: The Role of Mutagenesis in Rational Drug Discovery
“ A substitution of one amino acid by another in a protein can have effects ranging from negligible to dramatic, either locally or...

Cam Sinh Lu
Sep 3, 20244 min read


📢 GPCR Update: August 19-25, 2024 | Thrilling Announcement: New Pharmacology Course Dates & Exclusive Discounts Inside!
Dear GPCR Enthusiasts , Get ready for an exciting learning experience with our newly updated Principles of Pharmacology I & II Â courses!...

GPCR News
Aug 29, 20243 min read


📰 GPCR Weekly Buzz: Exciting Schedule Shifts for Principles of Pharmacology I & II | August 12-18, 2024
Dear GPCR Community, Before diving into this week's news, prepare for an incredible learning journey! We’ve made some updates to the Principles of Pharmacology I & II courses, and we can’t wait for you to join us on these new dates. Here’s the refreshed schedule: Principles of Pharmacology I October 3, 10, 17, 24 Principles of Pharmacology II October 31 November 7, 14, 21 December 5 As a premium member , you’re also unlocking over 500 minutes of exclusive, expert-led content

GPCR News
Aug 23, 20243 min read


📰 GPCR Buzz: August 5-11, 2024 | Top Highlights from DrGPCR University!
Dear GPCR Enthusiasts! Get ready to save the dates! Dr. GPCR University offers two live courses this fall that you won’t want to miss. Before the new semester kicks off, dive into our premium on-demand courses! With your membership, you’ll access over 500 minutes of top-notch content from Drs. Kenakin and Hoare on '  Applying Pharmacology to Drug Discovery ' and ' Advanced Data Analysis for GPCR Pharmacology .' Choose between our monthly or yearly plans (with a 5-day free tr

GPCR News
Aug 15, 20244 min read


Enhancing GPCR Research Outreach | Dr GPCR University early-bird registration ends soon!
📰 GPCR Weekly News, July 29 to August 4, 2024 Hey there, readers! Take a look at our GPCR coverage for this week. We've got 11 GPCR papers, seven industry news pieces, a new GPCR event, and even a job ad.  This week's highlight includes congrats to: Miles Thompson , Alexander Hauser , Caroline Gorvin ,  et al.  for their work on GPCR gene variants and human genetic disease Ilana Kotliar , Thomas Sakmar , et al. for their study on Multiplexed mapping of the interactome of

GPCR News
Aug 8, 20243 min read
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